Experimental Treatment Stops Brain Damage In Newborns

newbornAccording to researchers at Cincinnati Children’s Hospital Medical Center, suppressing an enzyme in the brains of newborns suffering from deprivation of oxygen and blood flow halts a type of brain damage that is the leading cause of cerebral palsy, mental retardation and death.

The scientists show blocking the brain enzyme, tissue-type plasminogen activator (tPA), prevents progressive brain damage triggered by the lack of oxygen and blood supply.

Chia-Yi Kuan, M.D. PhD, senior investigator on the study and a researcher in the divisions of Developmental Biology and Neurology at Cincinnati Children’s, said, “the experimental pre-clinical treatment involved putting a naturally occurring substance called plasminogen activator inhibitor-1 (PAI-1) into the brains of newborn rats”.

Source: EurekAlert


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